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P207 F9

SALSA MLPA Probemix P207 F9 detects copy number variations in the F7, F8 and F9 genes.

Specifications

Contents: 38 MLPA probes, including 11 probes for F7 (covering all exons), 7 probes for F8 and 10 probes for F9 (covering all exons).

Tissue: human genomic DNA.

Application: research on factor VII deficiency, hemophilia A, and hemophilia B.

For research use only (RUO). Not for use in diagnostics.

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Key related products

P011 VWF mix 1

Contains probes for the vWF gene, involved in von Willebrand factor deficiency.

P012 VWF mix 2

Contains probes for the vWF gene, involved in von Willebrand factor deficiency.

P178 F8

Contains probes for the F8 gene, involved in Hemophilia A.

View all

General information

The SALSA MLPA Probemix P207 F9 is a research use only (RUO) assay for the detection of deletions or duplications in the F7, F8 and F9 genes, encoding coagulation factors factor VII, factor VIII and factor IX, respectively.

Coagulation factors play an important role in bleeding control and vessel repair. Deficiency in any of these genes may results in a bleeding disorders with different clinical manifestation: F7 is involved in factor VII deficiency, F8 in hemophilia A, and F9 in hemophilia B. Both hemophilia A and B are inherited in an X-linked manner, while factor VII deficiency is inherited in an autosomal recessive fashion.

More information is available at https://ghr.nlm.nih.gov/gene/F7, https://www.ncbi.nlm.nih.gov/books/NBK1404/ and https://www.ncbi.nlm.nih.gov/books/NBK1495/.

Regulatory status

SALSA MLPA Probemix P207 F9 is for research use only (RUO) in all territories.

Product documentation

Version D1

Other versions

Contact us for earlier versions.

List prices

Product

Item no.
Description
Technology
Price
P207-025R
SALSA MLPA Probemix P207 F9 – 25 rxn
MLPA
€ 286.00
P207-050R
SALSA MLPA Probemix P207 F9 – 50 rxn
MLPA
€ 560.00
P207-100R
SALSA MLPA Probemix P207 F9 – 100 rxn
MLPA
€ 1096.00

Required reagents

A general SALSA MLPA Reagent Kit is required for MLPA experiments (to be ordered separately).

Item no.
Description
Technology
Price
EK1-FAM
SALSA MLPA Reagent Kit – 100 rxn – FAM (6 vials)
MLPA MS-MLPA
€ 348.00
EK1-CY5
SALSA MLPA Reagent Kit – 100 rxn – Cy5 (6 vials)
MLPA MS-MLPA
€ 348.00
EK5-FAM
SALSA MLPA Reagent Kit – 500 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK5-CY5
SALSA MLPA Reagent Kit – 500 rxn – Cy5 (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK20-FAM
SALSA MLPA Reagent Kit – 2000 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 6152.00

Price details & ordering

The prices above are list prices for direct orders from MRC Holland. Contact us for a quote that takes discounts and additional costs (such as shipping costs) into account. Different prices apply for orders through one of our sales partners; contact your local supplier for a quote.

More information about ordering & prices

Positive samples

Inclusion of a positive sample is usually not required, but can be useful for the analysis of your experiments. MRC Holland has very limited access to positive samples and cannot supply such samples. We recommend using positive samples from your own collection. Alternatively, you can use positive samples from an online biorepository, such as the Coriell Institute.

The commercially available positive samples below can be used with the current (D1) version of this product.

F7

F8

  • Coriell NA02325 (f): Heterozygous duplication affecting the probes for F8 Exon 1-17.

Resources

General MLPA resources

MLPA education

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