The importance of copy numbers in genetic diagnostics and research
Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.
MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.
Latest News
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Mar 03, 2026Updates to our DMD Portfolio
We are pleased to share an important update to our Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) portfolio. Improved versions of our MLPA assays for DMD copy number analysis are now available, offering enhanced performance and quality control. Read more.
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Feb 17, 2026New Product: NXtec D028 Carrier Panel 1
We are proud to introduce NXtec D028 Carrier Panel 1 - a high-throughput assay detecting CNVs and selected SNVs for carrier status analysis. Read more.
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Feb 16, 2026Our Products are IVDR-Certified!
We have successfully obtained our certification under the new In Vitro Diagnostic Regulation (IVDR; 2017/746)! The first batch of flagship products are already available on the market under the new IVDR, well in advance of the transition period deadline. Read more.
Come and Meet Us
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Mar 31, 2026 - 12:00–16:00 CET
Virtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net
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May 04, 2026 - Glasgow, UK
Visit us at SIOPE
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May 20, 2026 - Leuven, Belgium
Visit us at ISV
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May 26, 2026 - 16:00–20:00 CEST
Virtual Workshop: MLPA Raw Data Evaluation and Troubleshooting
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Jun 09, 2026 - 16:00–20:00 CEST
Virtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net