The importance of copy numbers in genetic diagnostics and research
Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.
MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.
Latest News
-
Nov 11, 2026Coming Soon: DM025 Developmental Disorders - One assay. Multiple mechanisms. Broader insight.
The upcoming NXtec-MS™ DM025 Developmental Disorders brings key targets together in a single assay, combining copy number and methylation analysis to provide a more comprehensive view of the genomic alterations associated with developmental disorders. Read more.
-
Nov 11, 2026New product: NXtec D038 Carrier Plus – Expanded coverage across 26 inherited disorders
The latest addition to MRC Holland’s digitalMLPA portfolio, NXtec™ D038 Carrier Plus, is a comprehensive high-throughput assay for carrier status determination. Read more.
-
Nov 05, 2026MRC Holland × GeneMind: digitalMLPA™ Validated on FASTASeq 300 and SURFSeq 5000
We are pleased to share the results of our collaboration with GeneMind, demonstrating the compatibility of digitalMLPA™ with the GeneMind FASTASeq 300 and SURFSeq 5000 sequencing platforms. Read more.
Come and Meet Us
-
Nov 10–14, 2026 · Seattle, USA
Visit us at AMP
-
Nov 20, 2026 · 10:00–14:00 CET
Virtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net
-
Jan 27–28, 2027 · London, UK
Visit us at Festival of Genomics
-
Feb 2, 2027 · 16:00–20:00 CET / 10 AM–2 PM EST
Virtual Workshop: MLPA Raw Data Evaluation and Troubleshooting
-
Feb 16, 2027 · 16:00–20:00 CET / 10 AM–2 PM EST
Virtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net