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MRC Holland: Confidence in Copy Number Determination

The importance of copy numbers in genetic diagnostics and research

Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.

MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.

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New & Improved Products

Improved Apr 06, 2021

SALSA MLPA Probemix P217 IGF1R

General information The SALSA MLPA Probemix P217 IGF1R is a research use only (RUO) assay for the detection of deletions or duplications in the IGF1R,, IGFBP3, ...

Improved Mar 23, 2021

SALSA MLPA Probemix ME031 GNAS

General information The SALSA MS-MLPA Probemix ME031 GNAS is a research use only (RUO) assay for the detection of aberrant methylation of one or more sequences ...

Improved Feb 05, 2021

SALSA MLPA Probemix P439 COL4A3

General information The SALSA MLPA Probemix P439 COL4A3 is a research use only (RUO) assay for the detection of deletions or duplications in the COL4A3 gene, ...

Improved Jan 27, 2021

SALSA MLPA Probemix ME034 Multi-locus Imprinting

General information The SALSA MS-MLPA Probemix ME034 Multi-locus Imprinting is a research use only (RUO) assay for the detection of aberrant methylation of one or more ...

Improved Jan 15, 2021

SALSA MLPA Probemix P329 CRLF2-CSF2RA-IL3RA

General information The SALSA MLPA Probemix P329 CRLF2-CSF2RA-IL3RA is a research use only (RUO) assay for the detection of deletions or duplications in the CRLF2, CSF2RA ...

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Improvements

Two target probes replaced and two added, eight reference probes replaced and one added.

Improvements

Eight target, one flanking, and four reference probes were replaced; two target and one reference pr

Improvements

Several target and reference probes were replaced and some probes changed in length.

Improvements

7 new target probes added, 3 reference probes and 1 digestion control probe replaced.

Improvements

One IL3RA probe and one flanking probe have been removed, and one flanking probe replaced.