The importance of copy numbers in genetic diagnostics and research
Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.
MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.
Latest News
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Mar 09, 2021Wanted: samples with aberrations in the AIP, LDLR, MEN1, or PKD1 genes
We are currently looking for DNA samples (1–5 µg) with copy number changes in the AIP, LDLR, MEN1, or PKD1 genes.
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Mar 09, 2021Learn more about SALSA digitalMLPA
Our new digitalMLPA™ technology is revolutionising large scale copy number variation detection. Learn more about the technique.
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Mar 09, 2021The power of MLPA in cancer analysis
A recent study from Soave et al. highlights the power of MLPA in a research setting for the analysis of copy number variation (CNV) in oncogenes and tumor suppressor genes in various sample DNA types.
Come and Meet Us
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Jul 15, 2021 - Online (starts 15:00 CEST; 10 PM BST/ART; 9 PM EDTA; 8 PM CDT/COT)
Virtual Workshop: MLPA Raw Data Evaluation and Troubleshooting
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Aug 28, 2021 - Online
ESHG
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Oct 26, 2021 - Online (starts 16:00 CEST; UTC+02:00)
Webinar: Get to Know digitalMLPA
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Nov 18, 2021 - Berlin, Germany
Workshop: "MLPA – Expert in a Day" – Germany
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Jan 27, 2022 - London, United Kingdom
The Festival of Genomics & Biodata