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MRC Holland: Confidence in Copy Number Determination

The importance of copy numbers in genetic diagnostics and research

Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.

MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.

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Latest News

  • May 20, 2020

    COVID-19 update

    Our products still remain available during the global coronavirus outbreak, but we may be difficult to reach by phone.

  • Mar 12, 2020

    COVID-19 concerns

    MRC Holland products remain available during the global coronavirus outbreak, but we may be more difficult to reach by phone.

  • Mar 12, 2020

    New product packaging

    All MRC Holland products are now shipped in new packaging that reflects the updated company style.

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New & Improved Products

Improved Jul 22, 2020

SALSA MLPA Probemix P099 GCH1-TH-SGCE-PRRT2

General information: The SALSA MLPA Probemix P099 GCH1-TH-SGCE-PRRT2 is a research use only (RUO) assay for the detection of deletions or duplications in the GCH1, ...

Improved Jun 26, 2020

SALSA MLPA Probemix P297 Microdeletion Syndromes-2

General information: The SALSA MLPA Probemix P297 Microdeletion Syndromes-2 is a research use only (RUO) assay for the detection of deletions or duplications in the ...

Improved Jun 18, 2020

SALSA MLPA Probemix P111 FCGR mix 2

General information: The SALSA MLPA Probemixes P110 FCGR mix 1 and P111 FCGR mix 2 are research use only (RUO) assays for the detection of ...

Improved Jun 18, 2020

SALSA MLPA Probemix P110 FCGR mix 1

General information: The SALSA MLPA Probemixes P110 FCGR mix 1 and P111 FCGR mix 2 are research use only (RUO) assays for the detection of ...

Improved Jun 15, 2020

SALSA MLPA Probemix P342 PKHD1 mix 2

General information: The SALSA MLPA Probemix P341/P342 PKHD1 is a research use only (RUO) assay for the detection of deletions or duplications in the PKHD1 ...

New Jun 08, 2020

SALSA MLPA Probemix P489 BARD1

General information: The SALSA MLPA Probemix P489 BARD1 is a research use only (RUO) assay for the detection of deletions or duplications in the BARD1 ...

Improved May 26, 2020

SALSA MLPA Probemix P088 Oligodendroglioma 1p-19q

Intended use: The SALSA MLPA Probemix P088 Oligodendroglioma 1p-19q is an in vitro diagnostic (IVD)1 or research use only (RUO) semi-quantitative assay2 for the detection ...

Improved May 19, 2020

SALSA MLPA Probemix P092 ABCC6

General information: The SALSA MLPA Probemix P092 ABCC6 is a research use only (RUO) assay for the detection of deletions or duplications in the ABCC6 ...

Improved May 07, 2020

SALSA MLPA Probemix P348 ATP1A2-CACNA1A-PRRT2

General information: The SALSA MLPA Probemix P438 ATP1A2-CACNA1A-PRRT2 is a research use only (RUO) assay for the detection of deletions or duplications in the ATP1A2, ...

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Improvements

Probes for PRRT2 have been added, four reference probes have been replaced and two removed.

Improvements

The probemix has been largely redesigned. Some regions coverage has been improved.

Improvements

The probemix has completely been redesigned.

Improvements

The probemix has completely been redesigned.

Improvements

One probe for PKHD1 has been removed and two reference probes have been replaced.

New Product

First released on Jun 08, 2020

Improvements

Three target and four reference probes have been replaced and one target probe is added.

Improvements

One flanking probe, one reference probe, one ABCC6 probe removed, seven reference probes replaced.

Improvements

Probes for PRRT2 have been added, four reference probes have been replaced and one removed, in addit