News Archive
Unlocking CNV Certainty: What We Shared at ESHG 2025
We were delighted to attend the 2025 edition of the European Human Genetics Conference in Milan, Italy - read further for our re-cap.
Here Comes the Sun – TERT Promoter Mutations in Skin Lesions
Testing for TERT promoter mutations in certain skin lesions can provide valuable insights - find out which MLPA probemixes can be used to test for these variants.
Documentation Update - digitalMLPA General Protocol
We’ve recently updated the digitalMLPA General Protocol to reflect a new recommendation for read depth - read more about this change.
Introducing NXtec: An Update to digitalMLPA Product Naming
Introducing NXtec—the new product line name for all currently available digitalMLPA assays. This change helps us clearly distinguish our current assays from future variants that may require different protocols or reagents.
Our Products are IVDR-Certified!
We have successfully obtained our certification under the new In Vitro Diagnostic Regulation (IVDR; 2017/746)! The first batch of flagship products are already available on the market under the new IVDR, well in advance of the transition period deadline.
Celebrating 40 Years of MRC Holland
This year marks the 40th anniversary of MRC Holland!
GENESUM - a Public-Private Collaboration Between MRC Holland and the LUMC
We are thrilled to announce a new public-private partnership between MRC Holland and the Leiden University Medical Center (LUMC).
Improved – P101 STK11 - Featuring New and Improved Denaturation Control Probes
P101 STK11, now available on the market under the IVDR, just received a major update, with the recently released C1 version displaying exceptional sensitivity in the detection of any denaturation issues. It features two improved and two newly added denaturation control probes, one target probe replacement, and a complete overhaul of the product's reference probes.
Documentation Update - Sequences Displayed in Probe Sequence Sheets (MLPA Probemixes)
We recently updated our probe sequence sheet template to display partial probe sequences in place of the full sequences. In the updated documentation, 20 nucleotides on either side of the probe's ligation site are displayed.
Improved – P148 TGFBR1-TGFBR2-TGFB2-SMAD3 – Featuring New Probes Targeting TGFB2 and SMAD3
The new C1 version of P148 TGFBR1-TGFBR2-TGFB2-SMAD3 is now available on the market, featuring several new probes targeting TGFB2 and SMAD3, and a number of improved target and reference probes that together increase the coverage and robustness of the probemix.