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News Archive

MLPA in Challenging Glioblastoma Cases

A brief research report published in Pathology & Oncology Research by researchers from the Czech Republic highlighted the inherent challenges of characterising glioblastoma by comparing multiple widely used methodologies, including MLPA.

Improved: P062 LDLR – Featuring a New Target Probe for Exon 18 of LDLR

P062 LDLR just received a major update, with the recently released E1 version featuring a new target probe for exon 18 of the LDLR gene.

New: P498 CSTB

P498 CSTB is a new assay developed to specifically detect deletions or duplications in the CSTB gene. 

New: P477 Head and Neck Carcinoma

New probemix: P477 Head and neck carcinoma targets the most frequently altered regions in HNSCCs and includes 36 probes for the CUL3, PIK3CA, SOX2, FAT1, KIAA0825, EGFR, SNAI2, NFIB, CCND1, FADD, TGIF1 and BCL2L1 genes.

A Year in Review – 2024

As we look back on 2024, we are excited to share some of the year’s highlights with you!

Upcoming Changes to MLPA Product Descriptions

In the coming years we will update product descriptions for SALSA® MLPA® products that are for in vitro diagnostic (IVD) use to a new structure and layout.

Implementation of Nationwide Newborn Screening for Spinal Muscular Atrophy in Serbia

Researchers from the University of Belgrade  succeeded in making state-wide newborn screening become a reality through a stepwise plan that included a laboratory validation step, a feasibility study on a smaller cohort of newborns, and finally the transition to a national program.  

Identification of a Distinct Subclass of Head and Neck Cancers

Researchers from the Amsterdam University Medical Centre recently published a study on a distinct subclass of head and neck cancers in collaboration with MRC Holland scientists.

P105 Glioma - Now Targeting Two Common TERT SNVs

P105 Glioma just received a major update that enables a more complete characterization of the genetic landscape of gliomas. The recently released E1 version includes two probes specific for the common TERT C228T and C250T SNVs.

ME034 Multi-Locus Imprinting - Now with Probes for ZNF597

ME034 Multi-locus Imprinting just received a major update, with the recently released D1 version featuring several new and improved target and reference probes that expand the differentially methylated regions investigated and ensure an even more robust assay output. 

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