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P297 Microdeletion Syndromes-2

SALSA MLPA Probemix P297 Microdeletion Syndromes-2 detects a subset of recurrent microdeletions and microduplications.

Specifications

Contents: 54 MLPA probes for the chromosomal regions 1q21.1, 3q29, 15q13, 15q24, 16p13.11, 16p12.1-p11.2, and 17q12.

Tissue: human genomic DNA.

Application: research on microdeletion and microduplication syndromes, including thrombocytopenia absent radius (TAR) syndrome, and Witteveen-Klok syndrome (WITKOS). See more information in the product description.

For research use only (RUO). Not for use in diagnostics.

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List Prices Documentation

Key related products

P245 Microdeletion Syndromes-1A

Targets several microdeletion/microduplication syndromes. Can be used for primary screening.

P064 Microdeletion Syndromes-1B

Targets 1p36 deletion, Wolf-Hirschhorn, Cri-du-Chat, Sotos, Saethre-Chotzen, Williams-Beuren, Langer-Giedion, WAGR, Prader-Willi/Angelman, Rubinstein-Taybi, Miller-Dieker, Smith-Magenis, Alagille, DiGeorge, and Phelan-McDermid syndrome.

P036 Subtelomeres Mix 1

Targets subtelomeric regions.

View all

General information

The SALSA MLPA Probemix P297 Microdeletion-2 is a research use only (RUO) assay for the detection of deletions or duplications in the following chromosomal regions:

  • 1q21.1 (TAR): 5 probes
  • 1q21.1 (distal): 6 probes
  • 3q29: 4 probes
  • 15q13: 10 probes
  • 15q24: 4 probes
  • 16p13.11: 4 probes
  • 16p12.1: 3 probes
  • 16p12.1-p11.2: 3 probes
  • 16p11.2 (distal): 3 probes
  • 16p11.2 (proximal): 4 probes
  • 17q12: 8 probes

More information about these Microdeletion Syndromes is available in Table 2 of the product description.

Regulatory status

SALSA MLPA Probemix P297 Microdeletion Syndromes-2 is for research use only (RUO) in all territories.

Product documentation

Version D1

Other versions

Contact us for earlier versions.

List prices

Product

Item no.
Description
Technology
Price
P297-025R
SALSA MLPA Probemix P297 Microdeletion Syndromes-2 – 25 rxn
MLPA
€ 286.00
P297-050R
SALSA MLPA Probemix P297 Microdeletion Syndromes-2 – 50 rxn
MLPA
€ 560.00
P297-100R
SALSA MLPA Probemix P297 Microdeletion Syndromes-2 – 100 rxn
MLPA
€ 1096.00

Required reagents

A general SALSA MLPA Reagent Kit is required for MLPA experiments (to be ordered separately).

Item no.
Description
Technology
Price
EK1-FAM
SALSA MLPA Reagent Kit – 100 rxn – FAM (6 vials)
MLPA MS-MLPA
€ 348.00
EK1-CY5
SALSA MLPA Reagent Kit – 100 rxn – Cy5 (6 vials)
MLPA MS-MLPA
€ 348.00
EK5-FAM
SALSA MLPA Reagent Kit – 500 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK5-CY5
SALSA MLPA Reagent Kit – 500 rxn – Cy5 (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK20-FAM
SALSA MLPA Reagent Kit – 2000 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 6152.00

Price details & ordering

The prices above are list prices for direct orders from MRC Holland. Contact us for a quote that takes discounts and additional costs (such as shipping costs) into account. Different prices apply for orders through one of our sales partners; contact your local supplier for a quote.

More information about ordering & prices

Positive samples

Inclusion of a positive sample is usually not required, but can be useful for the analysis of your experiments. MRC Holland has very limited access to positive samples and cannot supply such samples. We recommend using positive samples from your own collection. Alternatively, you can use positive samples from an online biorepository, such as the Coriell Institute.

The commercially available positive samples below can be used with the current (D1) version of this product.

Chromosome 3

Chromosome 15

  • Coriell NA03184: Heterozygous duplication affecting the probes for TJP1, ARHGAP11B, FAN1, TRPM1, KLF13, OTUD7A, CHRNA7, SCG5, PML, STRA6, EDC3 and SIN3A.

Chromosome 16

  • Coriell NA05875: Heterozygous deletion affecting the probes for IL21R, ATXN2L, RABEP2, LAT, MAZ, MVP, HIRIP3 and MAPK3.
  • Coriell NA06226: Heterozygous duplication affecting the probes for MARF1, MYH11, ABCC6, XYLT1, UQCRC2, VWA3A and CDR2.
  • Coriell NA08039: Heterozygous duplication affecting the probes for MARF1, MYH11, ABCC6, XYLT1, UQCRC2, VWA3A, CDR2, PALB2 and LCMT1.
  • Coriell NA13685: Heterozygous deletion affecting the probes for MARF1, MYH11 and ABCC6.

Resources

General MLPA resources

MLPA education

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