SALSA MLPA Probemix P078 Breast tumour detects copy number variations in genes and chromosomal regions associated with breast cancer.
Contents: 56 MLPA probes, including 42 probes for the following regions and genes: 6q (ESR1), 7p (EGFR), 8p (ZNF703, FGFR1, ADAM9, IKBKB), 8q (PRDM14, MTDH, MYC), 11q (CCND1, EMSY), 16q (CDH1), 17q (CPD, MED1, ERBB2, CDC6, TOP2A, MAPT, PPM1D, BIRC5), 19q12 (CCNE1), and 20q (AURKA).
Tissue: human genomic DNA, including DNA from FFPE tissue.
Application: research on breast cancer.
For research use only (RUO). Not for use in diagnostics.
SALSA MLPA Probemix P078 Breast tumour is a research use only (RUO) assay for the detection of deletions or amplifications in genes/chromosomal regions of diagnostic/clinical importance in breast cancer, including 6q (ESR1), 7p (EGFR), 8p (ZNF703, FGFR1, ADAM9, IKBKB), 8q (PRDM14, MTDH, MYC), 11q (CCND1, EMSY), 16q (CDH1), 17q (CPD, MED1, ERBB2, CDC6, TOP2A, MAPT, PPM1D, BIRC5), 19q (CCNE1) and 20q (AURKA). See Table 1 and Table 2 in the product description for more detailed information about all included chromosomal regions and genes.
SALSA MLPA Probemix P078 Breast tumour is for research use only (RUO) in all territories.
A general SALSA MLPA Reagent Kit is required for MLPA experiments (to be ordered separately).
The prices above are list prices for direct orders from MRC Holland. Contact us for a quote that takes discounts and additional costs (such as shipping costs) into account. Different prices apply for orders through one of our sales partners; contact your local supplier for a quote.
Inclusion of a positive sample is usually not required, but can be useful for the analysis of your experiments. MRC Holland has very limited access to positive samples and cannot supply such samples. We recommend using positive samples from your own collection. Alternatively, you can use positive samples from an online biorepository, such as the Coriell Institute.
See this support article for commercially available positive samples that can be used with this product.