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P239 BRCA1 region

SALSA® MLPA® Probemix P239 BRCA1 detects copy number variations in the BRCA1 region.

Specifications

Contents: 32 MLPA probes, including 11 probes for the region upstream of BRCA1, 5 probes for BRCA1 and 6 probes for the region downstream of BRCA1.

Tissue: human genomic DNA.

Application: research on hereditary breast and ovarian cancer (HBOC) syndrome.

For research use only (RUO). Not for use in diagnostics.

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List Prices Documentation

Key related products

P002 BRCA1

Contains probes for the BRCA1 gene, involved in breast and ovarian cancer. It should be used for primary screening of BRCA1.

P041 ATM-1

Contains probes for the ATM gene, involved in breast cancer and Ataxia Telangiectasia.

P042 ATM-2

Contains probes for the ATM gene, involved in breast cancer and Ataxia Telangiectasia.

View all

General information

The SALSA MLPA Probemix P239 BRCA1 region is a research use only (RUO) assay for the detection of deletions or duplications in the BRCA1 region, which is associated with hereditary breast and ovarian cancer.

Defects in the BRCA1 gene on human chromosome 17q21 are an important cause of hereditary breast and ovarian cancer. This SALSA MLPA Probemix P239 BRCA1 region can be used to characterise deletions/duplications that extend to the region up- and downstream of the BRCA1 gene. For primary screening of BRCA1, we recommend using SALSA MLPA Probemix P002 BRCA1. BRCA1 deletions and duplications detected using SALSA MLPA Probemix P002 BRCA1 can be confirmed with SALSA MLPA probemix P087 BRCA1 Confirmation. SALSA MLPA Probemix P239 BRCA1 region is developed for research purposes to investigate the extent of BRCA1 deletions/duplications.

More information is available at https://www.ncbi.nlm.nih.gov/books/NBK1247/

Regulatory status

SALSA MLPA Probemix P239 BRCA1 region is for research use only (RUO) in all territories.

Product documentation

Version C1

Other versions

Contact us for earlier versions.

List prices

Product

Item no.
Description
Technology
Price
P239-025R
SALSA MLPA Probemix P239 BRCA1 region – 25 rxn
MLPA
€ 286.00
P239-050R
SALSA MLPA Probemix P239 BRCA1 region – 50 rxn
MLPA
€ 560.00
P239-100R
SALSA MLPA Probemix P239 BRCA1 region – 100 rxn
MLPA
€ 1096.00

Required reagents

A general SALSA MLPA Reagent Kit is required for MLPA experiments (to be ordered separately).

Item no.
Description
Technology
Price
EK1-FAM
SALSA MLPA Reagent Kit – 100 rxn – FAM (6 vials)
MLPA MS-MLPA
€ 348.00
EK1-Cy5
SALSA MLPA Reagent Kit – 100 rxn – Cy5 (6 vials)
MLPA MS-MLPA
€ 348.00
EK5-FAM
SALSA MLPA Reagent Kit – 500 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK5-Cy5
SALSA MLPA Reagent Kit – 500 rxn – Cy5 (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK20-FAM
SALSA MLPA Reagent Kit – 2000 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 6152.00

Price details & ordering

The prices above are list prices for direct orders from MRC Holland. Contact us for a quote that takes discounts and additional costs (such as shipping costs) into account. Different prices apply for orders through one of our sales partners; contact your local supplier for a quote.

More information about ordering & prices

Positive samples

Inclusion of a positive sample is usually not required, but can be useful for the analysis of your experiments. MRC Holland has very limited access to positive samples and cannot supply such samples. We recommend using positive samples from your own collection. Alternatively, you can use positive samples from an online biorepository, such as the Coriell Institute.

We have no information about specific commercially available positive samples that can be used with this product.

Resources

General MLPA resources

MLPA education

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