digitalMLPA Applications
digitalMLPA™ is paving the way to unparalleled copy number detection by combining the trusted MLPA technology with the power of NGS. Explore our digitalMLPA panels on offer.
digitalMLPA products are for research use only. Not for use in diagnostic procedures.
NXtec D001 Hereditary Cancer Panel 1
NXtec D001 Hereditary Cancer Panel 1 is a cost-effective, focused panel that detects copy number variations in 28 key genes related to germline cancer. CNVs in these genes are associated with a hereditary predisposition to common cancer types including breast, ovarian, colorectal, gastric, prostate, pancreatic and endometrial cancer, and melanoma.
NXtec D002 Hereditary Cancer Panel 2
NXtec D002 Hereditary Cancer Panel 2 is a broad panel that detects copy number variations in 56 genes associated with a hereditary predisposition to a wide range of cancer types, including breast, ovarian, colorectal, gastric, prostate, pancreatic and endometrial cancer, melanoma, neurofibromatosis, retinoblastoma, Wilms' tumour, and many more.
NXtec D002 Hereditary Cancer Panel 2 is an extension of NXtec D001 Hereditary Cancer Panel 1, containing all target probes present in NXtec D001 Hereditary Cancer Panel 1 plus additional target probes, exclusive to NXtec D002 Hereditary Cancer Panel 2.
NXtec D006 Multiple Myeloma
D006 Multiple Myeloma detects copy number abnormalities on various chromosomal arms (1p, 1q, 13q, 17p) and in multiple-myeloma-associated genes. In addition, the panel detects trisomies, hyper- and hypodiploidy, and the BRAF V600E mutation associated with this malignancy.
NXtec D007 Acute Lymphoblastic Leukemia
D007 Acute Lymphoblastic Leukemia detects gains and losses in 73 specific target genes and 8 chromosomal regions (including 5q, iAMP21 and PAR1) associated with ALL. The panel can be used to examine intragenic copy number alterations, partial chromosome gains, losses and high-level amplifications, as well as gross ploidy changes and intrachromosomal gene fusions.
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