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P406 CMT2

SALSA MLPA Probemix P406 CMT2 detects copy number variations in the RAB7A, GARS, HSPB1, HSPB8 and SPTLC1 genes.

Specifications

Contents: 45 MLPA probes, including 6 probes for RAB7A, 17 probes for GARS, 3 probes for HSPB1, 2 probes for HSPB8, and 8 probes for SPTLC1.

Tissue: human genomic DNA.

Application: research on Charcot-Marie-Tooth hereditary axonal neuropathy type 2 (CMT2).

For research use only (RUO). Not for use in diagnostics.

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List Prices Documentation

Key related products

P033 CMT1

Contains probes to detect genes related to other (sub)types of CMT.

P143 MFN2-MPZ

Contains probes to detect genes related to other (sub)types of CMT.

P353 CMT4

Contains probes to detect genes involved in CMT4.

View all

General information

The SALSA MLPA Probemix P406 CMT2 is a research use only (RUO) assay for the detection of deletions or duplications in the RAB7A, GARS, HSPB1, HSPB8 and SPTLC1 genes, which are associated with Charcot-Marie-Tooth hereditary axonal neuropathy type 2.

Charcot-Marie-Tooth hereditary axonal neuropathy type 2 (CMT2) is characterised by distal muscle weakness and atrophy, mild sensory loss and normal or near normal nerve conduction velocities. CMT2 is clinically similar to CMT1, although typically less severe. There are several subtypes of CMT2, which are clinically alike and are only distinguished from each other by molecular genetic findings.

Regulatory status

SALSA MLPA Probemix P406 CMT2 is for research use only (RUO) in all territories.

Product documentation

Version A2

Other versions

Contact us for earlier versions.

List prices

Product

Item no.
Description
Technology
Price
P406-025R
SALSA MLPA Probemix P406 CMT2 – 25 rxn
MLPA
€ 296.00
P406-050R
SALSA MLPA Probemix P406 CMT2 – 50 rxn
MLPA
€ 580.00
P406-100R
SALSA MLPA Probemix P406 CMT2 – 100 rxn
MLPA
€ 1135.00

Required reagents

A general SALSA MLPA Reagent Kit is required for MLPA experiments (to be ordered separately).

Item no.
Description
Technology
Price
EK1-FAM
SALSA MLPA Reagent Kit – 100 rxn – FAM (6 vials)
MLPA MS-MLPA
€ 361.00
EK1-CY5
SALSA MLPA Reagent Kit – 100 rxn – Cy5 (6 vials)
MLPA MS-MLPA
€ 361.00
EK5-FAM
SALSA MLPA Reagent Kit – 500 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 1658.00
EK5-CY5
SALSA MLPA Reagent Kit – 500 rxn – Cy5 (5×6 vials)
MLPA MS-MLPA
€ 1658.00
EK20-FAM
SALSA MLPA Reagent Kit – 2000 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 6373.00

Price details & ordering

The prices above are list prices for direct orders from MRC Holland. Contact us for a quote that takes discounts and additional costs (such as shipping costs) into account. Different prices apply for orders through one of our sales partners; contact your local supplier for a quote.

More information about ordering & prices

Positive samples

Inclusion of a positive sample is usually not required, but can be useful for the analysis of your experiments. MRC Holland has very limited access to positive samples and cannot supply such samples. We recommend using positive samples from your own collection. Alternatively, you can use positive samples from an online biorepository, such as the Coriell Institute.

We have no information about specific commercially available positive samples that can be used with this product.

Resources

General MLPA resources

MLPA education

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