Choose your country to see the products for your location

P147 1p36

SALSA® MLPA® Probemix P147 1p36 detects copy number variations in the 1p36 subtelomeric region.

Specifications

SALSA® MLPA® Probemix P147 1p36 detects copy number variations in the 1p36 subtelomeric region.

Tissue: human genomic DNA.

Application: research on 1p36 deletion syndrome and characterization of copy number variations detected by P036 Subtelomeres Mix 1 and/or P070 Subtelomeres Mix 2B for research purposes.

For research use only (RUO). Not for use in diagnostics.

Quick links

List Prices Documentation

Key related products

P036 Subtelomeres Mix 1

This probemix contains one probe for every subtelomere.

P064 Microdeletion Syndromes-1B

Contains probes for different microdeletion and microduplication syndromes, including for the 1p36 region.

P070 Subtelomeres Mix 2B

This probemix contains one probe for every subtelomere.

View all

General information

The SALSA MLPA Probemix P147 1p36 is a research use only (RUO) assay for the detection of deletions or duplications in the 1p36 subtelomeric region, which are associated with the 1p36 deletion syndrome, also referred to as "monosomy 1p36". The P147 1p36 can be used to confirm and further characterise abnormalities detected by P036 Subtelomeres Mix 1 and/or P070 Subtelomeres Mix 2B.

1p36 deletion syndrome is a chromosome disorder where the end of the short arm of one of the two chromosomes is lost. The breakpoints for this cytogenetic syndrome are variable and range from bands 1p36.13 to 1p36.33 (Slavotinek et al. 1999). It is considered to be one of the most common chromosome terminal deletion syndromes and is a frequent cause of intellectual disability, although there is phenotypic variability based on the location and the extent of the deletions (Jordan et al. 2015). The incidence has been estimated to be 1 in 5,000 to 1 in 10,000 live born children (Gajecka et al. 2007). To date, more affected females than males have been reported.

Regulatory status

SALSA MLPA Probemix P147 1p36 is for research use only (RUO) in all territories.

Product documentation

Version C1

Other versions

Contact us for earlier versions.

List prices

Product

Item no.
Description
Technology
Price
P147-025R
SALSA MLPA Probemix P147 1p36 – 25 rxn
MLPA
€ 286.00
P147-050R
SALSA MLPA Probemix P147 1p36 – 50 rxn
MLPA
€ 560.00
P147-100R
SALSA MLPA Probemix P147 1p36 – 100 rxn
MLPA
€ 1096.00

Required reagents

A general SALSA MLPA Reagent Kit is required for MLPA experiments (to be ordered separately).

Item no.
Description
Technology
Price
EK1-FAM
SALSA MLPA Reagent Kit – 100 rxn – FAM (6 vials)
MLPA MS-MLPA
€ 348.00
EK1-Cy5
SALSA MLPA Reagent Kit – 100 rxn – Cy5 (6 vials)
MLPA MS-MLPA
€ 348.00
EK5-FAM
SALSA MLPA Reagent Kit – 500 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK5-Cy5
SALSA MLPA Reagent Kit – 500 rxn – Cy5 (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK20-FAM
SALSA MLPA Reagent Kit – 2000 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 6152.00

Price details & ordering

The prices above are list prices for direct orders from MRC Holland. Contact us for a quote that takes discounts and additional costs (such as shipping costs) into account. Different prices apply for orders through one of our sales partners; contact your local supplier for a quote.

More information about ordering & prices

Positive samples

Inclusion of a positive sample is usually not required, but can be useful for the analysis of your experiments. MRC Holland has very limited access to positive samples and cannot supply such samples. We recommend using positive samples from your own collection. Alternatively, you can use positive samples from an online biorepository, such as the Coriell Institute.

We have no information about specific commercially available positive samples that can be used with this product.

Resources

General MLPA resources

MLPA education

This site uses cookies to help improve your online experience. Learn more
No, thank you accept

Sign in

Don't have an account? Create one

Forgot password?

Select Your Country

Choose your country to see the products for your location