Choose your country to see the products for your location

SALSA MLPA Probemix P294 Tumour Loss

Tumour loss

Region: various

General information: The SALSA MLPA Probemix P294 Tumour Loss is a research use only (RUO) assay for the detection of copy number aberrations in 15 chromosomal regions, which are frequently deleted in tumour samples.

Probemix content: The SALSA MLPA Probemix P294-C1 Tumour Loss contains 63 MLPA probes with amplification products between 121 and 503 nucleotides (nt). This includes at least two probes for the following regions or genes: 1p36, 13q14 (RB1), AMER1, APC, BRCA1/2, CDKN2A/B, FHIT, FKBP8, NF1, PTCH1, PTEN, SMAD4, SMARCB1, STK11, TP53, TSC1/2, VHL, and WT1. In addition, 12 reference probes are included and detect different autosomal chromosomal locations which are relatively quiet in most tumour types. However, it should be noted that tumour karyotypes can harbour multiple numerical and structural aberrations, which can complicate interpretation of these reference probes. Complete probe sequences and the identity of the genes detected by the reference probes is available in Table 2b and online (www.mlpa.com).

This probemix contains nine quality control fragments generating amplification products between 64 and 105 nt: four DNA Quantity fragments (Q-fragments), two DNA Denaturation fragments (D-fragments), one Benchmark fragment, and one chromosome X and one chromosome Y-specific fragment (see table below). More information on how to interpret observations on these control fragments can be found in the MLPA General Protocol and online at www.mlpa.com.

Order Items

Probemix

Item no.
Description
Technology
Price
P294-025R
SALSA MLPA Probemix P294 Tumour Loss – 25 rxn
€ 243.00
P294-050R
SALSA MLPA Probemix P294 Tumour Loss – 50 rxn
€ 486.00
P294-100R
SALSA MLPA Probemix P294 Tumour Loss – 100 rxn
€ 972.00

Required Reagents (Sold Separately)

Item no.
Description
Technology
Price
EK1-FAM
SALSA MLPA EK1 reagent kit – 100 rxn – FAM
€ 300.00
EK1-Cy5
SALSA MLPA EK1 reagent kit – 100 rxn – Cy5
€ 300.00
EK5-FAM
SALSA MLPA EK5 reagent kit – 500 rxn – FAM
€ 1380.00
EK5-Cy5
SALSA MLPA EK5 reagent kit – 500 rxn – Cy5
€ 1380.00
EK20-FAM
SALSA MLPA EK20 reagent kit – 2000 rxn – FAM
€ 5295.00

Related Products

SALSA MLPA Probemix P175 Tumour Gain

Contains probes for MDM4, MYCN-ALK, PDGFRA, KIT, KDR, DHFR, EGFR, MET, SMO, BRAF/BRAF V600E mutation, FGFR1, MYC, ABL1, RET, CCND1/2, CDK4, MDM2, AURKB, ERBB2-TOP2A, AURKA and AR genes.

Sign in

Don't have an account? Create one

Forgot password?

Select Your Country

Choose your country to see the products for your location