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MRC Holland: Confidence in Copy Number Determination

The importance of copy numbers in genetic diagnostics and research

Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.

MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.

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New & Improved Products

Improved Oct 18, 2021

SALSA MLPA Probemix P429 SALSA MLPA probemix P429 SDHA-MAX-TMEM127

General information The SALSA MLPA Probemix P429 SDHA-MAX-TMEM127 is a research use only (RUO) assay for the detection of deletions or duplications in the SDHA, MAX ...

New Sep 23, 2021

SALSA MLPA Probemix P483 HER gene family

General information The SALSA MLPA Probemix P483 HER gene family is a research use only (RUO) assay for the detection of deletions or duplications in the ...

Improved Sep 07, 2021

SALSA MLPA Probemix P352 PKD1-PKD2

Intended purpose The SALSA MLPA Probemixes P351 PKD1 and P352 PKD1-PKD2 are in vitro diagnostic (IVD)1 or research use only (RUO) semi-quantitative assays2 for the detection ...

Improved Sep 07, 2021

SALSA MLPA Probemix P351 PKD1

Intended purpose The SALSA MLPA Probemixes P351 PKD1 and P352 PKD1-PKD2 are in vitro diagnostic (IVD)1 or research use only (RUO) semi-quantitative assays2 for the detection ...

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Improvements

Four probes for TMEM127 and two for SDHA added, one MAX probe replaced. Reference probes revised.

New Product

First released on Sep 23, 2021

Improvements

Three PKD1 probes and one PKD2 probe added. One PKD2 probe and one reference probe replaced.

Improvements

Two PKD1 probes added and two replaced. One TSC2 probe and four reference probes replaced.