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MRC Holland: Confidence in Copy Number Determination

The importance of copy numbers in genetic diagnostics and research

Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.

MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.

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New & Improved Products

Improved Sep 16, 2020

SALSA MLPA Probemix P301 Medulloblastoma mix 1

General information: The SALSA MLPA Probemix P301 Medulloblastoma mix 1 is a research use only (RUO) assay for the detection of deletions or duplications in ...

Improved Sep 01, 2020

SALSA MLPA Probemix P279 CACNA1A

General information: The SALSA MLPA Probemix P279 CACNA1A is a research use only (RUO) assay for the detection of deletions or duplications in the genes ...

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Improvements

Several reference probes have been replaced and several probes have a change in length.

Improvements

Three target probes added, one target probe replaced. Two reference probes removed and four modified