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The importance of copy numbers in genetic diagnostics and research
Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.
MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.
Latest News
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Feb 06, 2025
Our Products are IVDR-Certified!
We have successfully obtained our certification under the new In Vitro Diagnostic Regulation (IVDR; 2017/746)! The first batch of flagship products are already available on the market under the new IVDR, well in advance of the transition period deadline.
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Feb 04, 2025
Improved – ME033 TNDM – Featuring Updated Target and Reference Probes
ME033 TNDM just received a major update with version B1 featuring the addition of five new target probes and the replacement of seven target probes as well as all ten reference probes, further refining the performance of the probemix in order to detect the majority of TNDM cases.
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Feb 03, 2025
MLPA in Challenging Glioblastoma Cases
A brief research report published in Pathology & Oncology Research by researchers from the Czech Republic highlighted the inherent challenges of characterising glioblastoma by comparing multiple widely used methodologies, including MLPA.
Come and Meet Us
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Feb 25, 2025 - 16:00–20:00 CET
Virtual Workshop: MLPA Raw Data Evaluation and Troubleshooting
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Mar 11, 2025 - 16:00–20:00 CET
Virtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net
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Mar 19, 2025 - 10:00–14:00 CET
Virtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net
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Apr 02, 2025 - Innsbruck, Austria
Visit us at GfH
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May 12, 2025 - Budapest, Hungary
Visit us at SIOPE