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MRC Holland: Confidence in Copy Number Determination

The importance of copy numbers in genetic diagnostics and research

Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.

MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.

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Latest News

  • Feb 06, 2025

    Our Products are IVDR-Certified!

    We have successfully obtained our certification under the new In Vitro Diagnostic Regulation (IVDR; 2017/746)! The first batch of flagship products are already available on the market under the new IVDR, well in advance of the transition period deadline. 

  • Feb 04, 2025

    Improved – ME033 TNDM – Featuring Updated Target and Reference Probes

    ME033 TNDM just received a major update with version B1 featuring the addition of five new target probes and the replacement of seven target probes as well as all ten reference probes, further refining the performance of the probemix in order to detect the majority of TNDM cases.

  • Feb 03, 2025

    MLPA in Challenging Glioblastoma Cases

    A brief research report published in Pathology & Oncology Research by researchers from the Czech Republic highlighted the inherent challenges of characterising glioblastoma by comparing multiple widely used methodologies, including MLPA.

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