The importance of copy numbers in genetic diagnostics and research
Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.
MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.
Latest News
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                            								 Oct 20, 2025 Oct 20, 2025Our Products are IVDR-Certified!We have successfully obtained our certification under the new In Vitro Diagnostic Regulation (IVDR; 2017/746)! The first batch of flagship products are already available on the market under the new IVDR, well in advance of the transition period deadline. 
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                            								 Oct 14, 2025 Oct 14, 2025New Product Launch: NXtec D002 Hereditary Cancer Panel 2 for Broad Hereditary Cancer AnalysisIntroducing NXtec Hereditary Cancer Panel 2 – a broad panel for the detection of CNVs in cancer-associated genes and the presence of selected variants. 
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                            								 Oct 02, 2025 Oct 02, 2025Improved – P242 Pancreatitis – Now Featuring Mutation-Specific Probes for SPINK1 and PRSS1P242 Pancreatitis just received a major update, with the recently released D1 version featuring nine new target probes and three new mutation-specific probes, as well as three replaced target probes and eight replaced reference probes. The updated probe content facilitates enhanced detection of HP-related genetic alterations and improves assay robustness. 
Come and Meet Us
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                                Nov 06, 2025 - 16:00-20:00 CETVirtual Workshop: MLPA Raw Data Evaluation and Troubleshooting
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                                Nov 11, 2025 - Boston, USAVisit us at AMP 2025
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                                Nov 20, 2025 - 16:00-20:00 CETVirtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net
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                                Jan 28, 2026 - London, UKVisit us at Festival of Genomics
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                                Feb 04, 2026 - 10:00–14:00 CETVirtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net
