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P181 Centromere mix 1

SALSA MLPA Probemix P181 Centromere mix 1 detects copy number variations in genes close to the centromeres of all chromosomes except the Y-chromosome.

Specifications

Contents: 46 MLPA probes, including probes for each chromosome arm except for the Y-chromosome and the p-arms of the acrocentric chromosomes (13, 14, 15, 21 and 22).

Tissue: human genomic DNA, including DNA from FFPE tissue.

Application: research, which may include research on cancer, characterisation of marker chromosomes, and aneuploidies.

For research use only (RUO). Not for use in diagnostics.

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List Prices Documentation

Key related products

P182 Centromere mix 2

Targets different sequences in the same region as compared to P181 Centromere mix 1.

P095 Aneuploidy

Targets chromosomes 13, 18, 21, X and Y.

P036 Subtelomeres Mix 1

Targets subtelomeric regions and the centromeric regions of the five acrocentric chromosomes. Targets differ from P070 Subtelomeres Mix 2B.

P070 Subtelomeres Mix 2B

Targets subtelomeric regions and the centromeric regions of the five acrocentric chromosomes. Targets differ from P036 Subtelomeres Mix 1.

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General information

The SALSA MLPA Probemix P181 Centromere mix 1 is a research use only (RUO) assay for the detection of deletions or duplications in genes close to the centromeres of all chromosomes, with the exception of the Y-chromosome. In most cases, probes are included for the first well-characterised gene in the centromeric region. Possible applications of this probemix are in cancer research, as well as for characterisation of marker chromosomes and the detection of aneuploidies.

Regulatory status

SALSA MLPA Probemix P181 Centromere mix 1 is for research use only (RUO) in all territories.

Product documentation

Version C1

Other versions

Contact us for earlier versions.

List prices

Product

Item no.
Description
Technology
Price
P181-025R
SALSA MLPA Probemix P181 Centromere mix 1 – 25 rxn
MLPA
€ 296.00
P181-050R
SALSA MLPA Probemix P181 Centromere mix 1 – 50 rxn
MLPA
€ 580.00
P181-100R
SALSA MLPA Probemix P181 Centromere mix 1 – 100 rxn
MLPA
€ 1135.00

Required reagents

A general SALSA MLPA Reagent Kit is required for MLPA experiments (to be ordered separately).

Item no.
Description
Technology
Price
EK1-FAM
SALSA MLPA Reagent Kit – 100 rxn – FAM (6 vials)
MLPA MS-MLPA
€ 361.00
EK1-CY5
SALSA MLPA Reagent Kit – 100 rxn – Cy5 (6 vials)
MLPA MS-MLPA
€ 361.00
EK5-FAM
SALSA MLPA Reagent Kit – 500 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 1658.00
EK5-CY5
SALSA MLPA Reagent Kit – 500 rxn – Cy5 (5×6 vials)
MLPA MS-MLPA
€ 1658.00
EK20-FAM
SALSA MLPA Reagent Kit – 2000 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 6373.00

Price details & ordering

The prices above are list prices for direct orders from MRC Holland. Contact us for a quote that takes discounts and additional costs (such as shipping costs) into account. Different prices apply for orders through one of our sales partners; contact your local supplier for a quote.

More information about ordering & prices

Positive samples

Inclusion of a positive sample is usually not required, but can be useful for the analysis of your experiments. MRC Holland has very limited access to positive samples and cannot supply such samples. We recommend using positive samples from your own collection. Alternatively, you can use positive samples from an online biorepository, such as the Coriell Institute.

We have no information about specific commercially available positive samples that can be used with this product.

Resources

General MLPA resources

MLPA education

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