Coming Soon: DM025 Developmental Disorders - One assay. Multiple mechanisms. Broader insight.
The latest addition to MRC Holland’s digitalMLPA portfolio, NXtec™ D038 Carrier Plus, is a comprehensive high-throughput assay for carrier status determination.
Developmental disorders can result from a wide range of genomic alterations, including methylation abnormalities, recurrent copy number changes, and chromosomal imbalances. Yet these changes are often studied using multiple assays.
To help address this complexity, digitalMLPA™ NXtec-MS™ DM025 Developmental Disorders brings key targets together in a single assay, combining copy number and methylation analysis to provide a more comprehensive view of the genomic alterations associated with developmental disorders.
DM025 targets:
- Imprinting-associated differentially methylated regions (iDMRs)
- Fragile X-associated methylation analysis through the FMR1 region
- Recurrent microdeletion and microduplication regions
- Genome-wide subtelomeric and selected centromeric regions
Enabling broader insight into developmental disorders, DM025 offers:
- Comprehensive coverage of key genomic regions associated with a broad range of developmental disorders
- Robust analysis of CNVs and methylation status in a single workflow
- Bisulfite-free methylation status determination
- Simple data analysis using dedicated software; no bioinformatics needed
Be among the first to hear when DM025 Developmental Disorders becomes available!