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We are proud to announce the launch of a new MLPA probemix, P483 HER gene family. The HER gene family consists of four tyrosine kinase receptors: EGFR (ERBB1/HER1), ERBB2 (HER2), ERBB3 (HER3) and ERBB4 (HER4). EGFR amplifications play a role in a range of cancers, including colorectal carcinoma, glioblastoma and non-small-cell lung carcinoma.
SALSA MLPA probemix P483 HER gene family is a research use only (RUO) assay for the simultaneous detection of copy number changes of the four aforementioned genes. In addition, this new probemix contains probes upstream and downstream of the HER genes to better assess the extent of possible duplications and deletions. The assay also includes several probes targeting the CEP17 region and the opposite chromosomal arm 17p to distinguish between ERBB2 amplification and chromosome 17 polysomy.
This product is for Research Use Only. Not for use in diagnostic procedures.